Vikings vs. Colts prediction, odds, line, spread: 2022 NFL picks, Week 15 best bets by model on 157-113 run

Vikings-Colts: 5 things you can count on If the Vikings can hit Matt Ryan there's a good chance he'll fumble.

Minneapolis, Minnesota, USA; Indianapolis Colts safety Julian Blackmon (32) makes an interception against the Minnesota Vikings

Minneapolis, Minnesota, USA; Minnesota Vikings running back Dalvin Cook (4) is stopped on a fourth down run against the Indianapolis Colts

Minneapolis, Minnesota, USA; Indianapolis Colts running back Deon Jackson (35) makes a catch for a touchdown

Minneapolis, Minnesota, USA; Minnesota Vikings punter Ryan Wright (14) reacts after throwing an incomplete pass